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CD8A Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89114946 Shop All Abnova Corporation Products
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89-114-946 100 μL
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Catalog No. 89-114-946 Supplier Abnova Corporation Supplier No. PAB11235

Description

Rabbit polyclonal antibody raised against synthetic peptide of CD8A.

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen CD8A
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CD8A.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:200) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene CD8A
Gene Alias CD8/Leu2/MAL/p32
Gene Symbols CD8A
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human CD8A.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 925
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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