CD8B, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CD8B.

Supplier:  Abnova Corporation PAB3088

Catalog No. 89-130-824

Description

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq

Specifications

• Antigen: CD8B
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CD8B.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_004922;P10966
• Gene Symbols: CD8B
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CD8B.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) Flow cytometry (1:10-50) The optimal working dilution should be determined by the end user.
• Gene: CD8B
• Gene Alias: CD8B1/LYT3/Leu2/Ly3/MGC119115
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 926
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only