CDC2, Rabbit, Clone: SP80, Abnova™

Rabbit monoclonal antibody raised against synthetic peptide of CDC2.

Supplier:  Abnova Corporation MAB10034

Catalog No. 89-108-349

Description

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CDC2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
• Gene: CDC2
• Gene Symbols: CDC2
• Immunogen: A synthetic peptide corresponding to C-terminus of human CDC2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Clone: SP80
• Description: Rabbit monoclonal antibody raised against synthetic peptide of CDC2.
• Formulation: In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
• Gene Alias: CDC28A/CDK1/DKFZp686L20222/MGC111195
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 983
• Content And Storage: Store at 4°C. Do not freeze.

For Research Use Only