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CDC2 (phospho T161), Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89114223 Shop All Abnova Corporation Products
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89-114-223 400 μL
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Catalog No. 89-114-223 Supplier Abnova Corporation Supplier No. PAB0434

Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDC2.

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen CDC2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description cell division cycle 2, G1 to S and G2 to M
Formulation In PBS (0.09% sodium azide)
Gene CDC2
Gene Accession No. NP_001777;P06493
Gene Alias CDC28A, CDK1, DKFZp686L20222, MGC111195
Gene Symbols CDC2
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T161 of human CDC2.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 983
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Purified
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