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CDC27 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89120763 Shop All Abnova Corporation Products
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89-120-763 100 μg
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Catalog No. 89-120-763 Supplier Abnova Corporation Supplier No. PAB19233
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Description

Rabbit polyclonal antibody rasied against synthetic peptide of CDC27.

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen CDC27
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody rasied against synthetic peptide of CDC27.
Dilution Western Blot (1-2 ug/mL) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene CDC27
Gene Accession No. NP_001247
Gene Alias APC3/CDC27Hs/D0S1430E/D17S978E/HNUC
Gene Symbols CDC27
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 19 amino acids near C-terminus of human CDC27.
Purification Method Peptide affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 996
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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