CDC2L2, Rabbit, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against recombinant CDC2L2.
Supplier: Abnova Corporation PAB27486
This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far. [provided by RefSeqSequence: YRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARREWERQKRREMAEHSRRERDRLE
|Rabbit polyclonal antibody raised against recombinant CDC2L2.
|In PBS, pH 7.2, (40% glycerol, 0.02% sodium azide)
|Antigen affinity purification
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunofluorescence, Immunohistochemistry (PFA fixed)
|Immunohistochemistry (1:50-1:200) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user.
|Recombinant protein corresponding to amino acids of human CDC2L2.
For Research Use Only