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CDC42 Rabbit anti-Bovine, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89120632 Shop All Abnova Corporation Products
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100 μg
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89-120-632 100 μg
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Catalog No. 89-120-632 Supplier Abnova Corporation Supplier No. PAB19100
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Rabbit polyclonal antibody raised against synthetic peptide of CDC42.

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq

Specifications

Antigen CDC42
Applications Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CDC42.
Dilution Western Blot (0.1-0.5 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Gene CDC42
Gene Alias CDC42Hs/G25K
Gene Symbols CDC42
Host Species Rabbit
Immunogen A synthetic peptide corresponding to internal region of human CDC42.
Purification Method Immunoaffinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 998
Target Species Bovine, Human, Mouse, Rat
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG
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