CDC6 Rabbit anti-Human, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of CDC6.
Manufacturer: Abnova Corporation PAB24908
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of CDC6.|
|In PBS, pH 7.2 (0.05% sodium azide)|
|A synthetic peptide corresponding to CDC6.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|CDC6 polyclonal antibody detects endogenous levels of CDC6 protein.|
|Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.|
|Antigen affinity purification|
For Research Use Only