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CDH1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126485 Shop All Abnova Corporation Products
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89-126-485 100 μL
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Catalog No. 89-126-485 Supplier Abnova Corporation Supplier No. PAB24814
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CDH1.

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq

Specifications

Antigen CDH1
Applications Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CDH1.
Dilution Western Blot (1:500-1:1000) Immunofluorescence (1:50-1:200) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene CDH1
Gene Alias Arc-1/CD324/CDHE/ECAD/LCAM/UVO
Gene Symbols CDH1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to CDH1.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 999
Test Specificity CDH1 polyclonal antibody detects endogenous levels of CDH1 protein.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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