CDH1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-852	400 μL

Catalog No. 89-130-852 Supplier Abnova Corporation Supplier No. PAB3139

Description

Rabbit polyclonal antibody raised against synthetic peptide of CDH1.

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq

Specifications

• Antigen: CDH1
• Applications: Flow Cytometry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CDH1.
• Dilution: Western Blot (1:1000) Flow cytometry (1:10-50) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: CDH1
• Gene Accession No.: NP_004351;P12830
• Gene Alias: Arc-1/CD324/CDHE/ECAD/LCAM/UVO
• Gene Symbols: CDH1
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDH1.
• Purification Method: Protein A purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 999
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only