CDH8, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CDH8.

Supplier:  Abnova Corporation PAB2476

Catalog No. 89-126-427

Description

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq]

Specifications

• Antigen: CDH8
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CDH8.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_001787;P55286
• Gene Symbols: CDH8
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDH8.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
• Gene: CDH8
• Gene Alias: Nbla04261
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1006
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only