CDK8 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CDK8.

Supplier:  Abnova Corporation PAB26859

Catalog No. 89-128-504

Description

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq]

Specifications

• Antigen: CDK8
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CDK8.
• Formulation: In PBS, pH 7.2 (0.09% sodium azide)
• Gene Accession No.: P49336
• Gene Symbols: CDK8
• Immunogen: A synthetic peptide corresponding to human CDK8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: CDK8 polyclonal antibody detects endogenous levels of CDK8 protein.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Gene: CDK8
• Gene Alias: K35/MGC126074/MGC126075
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1024
• Target Species: Human, Mouse
• Form: Liquid

For Research Use Only