CDKN1B Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CDKN1B.

Supplier:  Abnova Corporation PAB5497

Catalog No. 89-131-880

Description

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq

Specifications

• Antigen: CDKN1B
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CDKN1B.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: CDKN4/KIP1/MEN1B/MEN4/P27KIP1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene: CDKN1B
• Gene Symbols: CDKN1B
• Immunogen: A synthetic peptide corresponding to residues surrounding S10 of human CDKN1B.
• Regulatory Status: RUO
• Gene ID (Entrez): 1027
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only