CDKN1B (phospho T157), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDKN1B.

Supplier:  Abnova Corporation PAB0559

Catalog No. 89-114-276

Description

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq

Specifications

• Antigen: CDKN1B
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDKN1B.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_004055;P46527
• Gene Symbols: CDKN1B
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T157 of human CDKN1B.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: CDKN1B
• Gene Alias: CDKN4/KIP1/MEN1B/MEN4/P27KIP1
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1027
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only