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Description
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
Specifications
Specifications
| Antigen | CDX2 |
| Applications | Immunohistochemistry |
| Classification | Monoclonal |
| Clone | EPR2764Y |
| Conjugate | Unconjugated |
| Description | Rabbit monoclonal antibody raised against CDX2. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (protein base, 0.09% sodium azide) |
| Gene | CDX2 |
| Gene Alias | CDX-3/CDX3 |
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For Research Use Only
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