CELSR1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-127-794	50 μg

Catalog No. 89-127-794 Supplier Abnova Corporation Supplier No. PAB26154

Description

Rabbit polyclonal antibody raised against synthetic peptide of CELSR1.

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq

Specifications

• Antigen: CELSR1
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CELSR1.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15-20 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: CELSR1
• Gene Accession No.: Q9NYQ6
• Gene Alias: CDHF9/DKFZp434P0729/FMI2/HFMI2/ME2
• Gene Symbols: CELSR1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 15 amino acids at extracellular domain of human CELSR1.
• Purification Method: Immunoaffinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9620
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CELSR2 (60%).
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only