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Description
Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | CES1 |
| Applications | ELISA, Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | carboxylesterase 1 (monocyte/macrophage serine esterase 1) |
| Formulation | In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide) |
| Gene | CES1 |
| Gene Alias | ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH |
| Gene Symbols | CES1 |
| Host Species | Rabbit |
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