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Description
Changes in gene expression are associated with changes in chromatin structure, which can result from modification of histones by acetylation and methylation. In addition, SWI/SNF proteins can effect chromatin structure and gene expression by causing ATP-dependent disruption of the nucleosome and by enhancing binding of transcription factors. CHD5 belongs to a group of SWI/SNF proteins called CHD proteins, which contain a SWI/SNF-like helicase/ATPase domain, as well as a DNA-binding domain and a chromodomain that directly modifies chromatin structure (Thompson et al., 2003 [PubMed 12592387]).[supplied by OMIM
Specifications
Specifications
| Antigen | CHD5 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of CHD5. |
| Dilution | ELISA (1:500-1:1000) Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In serum (0.05% sodium azide) |
| Gene | CHD5 |
| Gene Accession No. | Q8TDI0 |
| Gene Alias | DKFZp434N231/KIAA0444 |
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