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CNTFR Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89120361 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-120-361 100 μg
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Catalog No. 89-120-361 Supplier Abnova Corporation Supplier No. PAB18803
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CNTFR.

This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq

Specifications

Antigen CNTFR
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CNTFR.
Dilution ELISA (1:8000-1:30000) Western Blot (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In buffer containing 0.02% sodium azide, 2% BSA
Gene CNTFR
Gene Alias MGC1774
Gene Symbols CNTFR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 14 amino acids at internal region of human CNTFR.
Purification Method Peptide affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1271
Target Species Human
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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