COL4A4, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of COL4A4.

Supplier:  Abnova Corporation PAB17512

Catalog No. 89-119-175

Description

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR. [provided by RefSeq]

Specifications

• Antigen: COL4A4
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of COL4A4.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene Accession No.: P53420
• Gene Symbols: COL4A4
• Immunogen: A synthetic peptide corresponding to internal of human COL4A4.
• Regulatory Status: RUO
• Gene ID (Entrez): 1286
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:500) ELISA (1:1000) The optimal working dilution should be determined by the end user.
• Gene: COL4A4
• Gene Alias: CA44
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of total COL4A4 protein.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only