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COPS5 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115290 Shop All Abnova Corporation Products
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100 μL
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89-115-290 100 μL
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Catalog No. 89-115-290 Supplier Abnova Corporation Supplier No. PAB11685

Description

Rabbit polyclonal antibody raised against synthetic peptide of COPS5.

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq

Specifications

Antigen COPS5
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of COPS5.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene COPS5
Gene Alias CSN5/JAB1/MGC3149/MOV-34/SGN5
Gene Symbols COPS5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human COPS5.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10987
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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