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CRH Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126616 Shop All Abnova Corporation Products
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100 μL
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89-126-616 100 μL
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Catalog No. 89-126-616 Supplier Abnova Corporation Supplier No. PAB24940
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CRH.

Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition. [provided by RefSeq

Specifications

Antigen CRH
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CRH.
Dilution Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene CRH
Gene Alias CRF
Gene Symbols CRH
Host Species Rabbit
Immunogen A synthetic peptide corresponding to CRH.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1392
Test Specificity CRH polyclonal antibody detects endogenous levels of CRH.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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