CRIM1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-127-117	100 μg

Catalog No. 89-127-117 Supplier Abnova Corporation Supplier No. PAB25500

Description

Rabbit polyclonal antibody raised against synthetic peptide of CRIM1.

Motor neurons are among the earliest neurons to appear after the commencement of cell patterning and the beginning of cell differentiation. Differentiation occurs in a ventral-to-dorsal gradient and is mediated, at least in part, by the concentration of ventrally expressed Sonic hedgehog protein (SHH; MIM 600725). Dorsally expressed factors, such as members of the bone morphogenic protein (e.g., BMP4; MIM 112262) and transforming growth factor-beta (e.g., TGFB1; MIM 190180) families, can repress the induction of these neurons. CRIM1 may interact with growth factors implicated in motor neuron differentiation and survival (Kolle et al., 2000 [PubMed 10642437]).[supplied by OMIM

Specifications

• Antigen: CRIM1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CRIM1.
• Dilution: Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: CRIM1
• Gene Accession No.: NP_057525
• Gene Alias: MGC138194/S52
• Gene Symbols: CRIM1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to C-terminus of human CRIM1.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51232
• Test Specificity: CRIM1 antibody is human reactive. CRIM1 antibody is predicted to not cross-react with CRIM2.
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only