CRK Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-119-692	100 μg

Catalog No. 89-119-692 Supplier Abnova Corporation Supplier No. PAB18119

Description

Rabbit polyclonal antibody raised against synthetic peptide of CRK.

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq

Specifications

• Antigen: CRK
• Applications: ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CRK.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: CRK
• Gene Accession No.: P46108
• Gene Alias: CRKII
• Gene Symbols: CRK
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to human CRK.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1398
• Test Specificity: This antibody is specific to CRK.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only