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CSE1L Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89114926 Shop All Abnova Corporation Products
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89-114-926 100 μL
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Catalog No. 89-114-926 Supplier Abnova Corporation Supplier No. PAB11210

Rabbit polyclonal antibody raised against synthetic peptide of CSE1L.

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq

Specifications

Antigen CSE1L
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CSE1L.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene CSE1L
Gene Alias CAS/CSE1/MGC117283/MGC130036/MGC130037/XPO2
Gene Symbols CSE1L
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human CSE1L.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1434
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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