CSF1R (phospho Y561), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CSF1R.

Supplier:  Abnova Corporation PAB29277

Catalog No. 89-130-714

Description

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq

Specifications

• Antigen: CSF1R
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CSF1R.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: P07333
• Gene Symbols: CSF1R
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y561 of human CSF1R.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: CSF1R (phospho Y561) polyclonal antibody detects endogenous levels of human CSF1R only when phosphorylated at tyrosine 561.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.
• Gene: CSF1R
• Gene Alias: C-FMS/CD115/CSFR/FIM2/FMS
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1436
• Target Species: Human, Mouse
• Form: Liquid

For Research Use Only