CSF1R (phospho Y561), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-714	100 μL

Catalog No. 89-130-714 Supplier Abnova Corporation Supplier No. PAB29277

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CSF1R.

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq

Specifications

• Antigen: CSF1R
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CSF1R.
• Dilution: Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: CSF1R
• Gene Accession No.: P07333
• Gene Alias: C-FMS/CD115/CSFR/FIM2/FMS
• Gene Symbols: CSF1R
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y561 of human CSF1R.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1436
• Test Specificity: CSF1R (phospho Y561) polyclonal antibody detects endogenous levels of human CSF1R only when phosphorylated at tyrosine 561.
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only