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CST3, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CST3.

Manufacturer:  Abnova Corporation PAB19103

Catalog No. 89-120-635

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq

Specifications

Specifications

CST3
Unconjugated
Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) Immunocytochemistry (1 ug/mL) The optimal working dilution should be determined by the end user.
CST3
ARMD11|MGC117328
Rabbit
IgG
100 ug
Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL
Polyclonal
Human
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Rabbit polyclonal antibody raised against synthetic peptide of CST3.
Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Lyophilized
CST3
A synthetic peptide corresponding to C-terminus of human CST3.
Immunoaffinity purification
RUO
Primary
1471
SDS
Documents
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