CST3, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-635	100 μg

Catalog No. 89-120-635 Supplier Abnova Corporation Supplier No. PAB19103

Description

Rabbit polyclonal antibody raised against synthetic peptide of CST3.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq

Specifications

• Antigen: CST3
• Applications: Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CST3.
• Dilution: Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) Immunocytochemistry (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 0.9mg NaCl, 0.2mg Na₂HPO₄ (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
• Gene: CST3
• Gene Alias: ARMD11/MGC117328
• Gene Symbols: CST3
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to C-terminus of human CST3.
• Purification Method: Immunoaffinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1471
• Target Species: Human
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG

For Research Use Only