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CTCF, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89121452 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-121-452 100 μg
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Catalog No. 89-121-452 Supplier Abnova Corporation Supplier No. PAB19945
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CTCF.

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. [provided by RefSeq]

Specifications

Antigen CTCF
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CTCF.
Dilution ELISA (1:200000-1:250000) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)
Gene CTCF
Gene Symbols CTCF
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human CTCF.
Purification Method Immunoaffinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10664
Test Specificity This antibody reacts with endogenous CTCF protein. A BLAST analysis was used to suggest reactivity with CTCF from human, mouse, horse, bovine, panda, rabbit, Danio, and chicken based on a 100% homology with the immunizing sequence. Cross-reactivity with CTCF from other sources has not been determined.
Target Species Human, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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