CTNNB1 (phospho S33/37), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CTNNB1.
Manufacturer: Abnova Corporation PAB12604
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIMSequence: SGIHS
|Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.|
|Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
|This antibody recognizes ~88 KDa of human CTNNB1.|
|Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot|
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of CTNNB1.|
|In TBS, pH 7.2 (BSA, 10% Proclin300)|
|Synthetic phosphopeptide corresponding to residues surrounding S33/S37 of human CTNNB1.|
|Human, Murine, Rat|
For Research Use Only