CTNNB1 (phospho S33/37), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of CTNNB1.

Supplier:  Abnova Corporation PAB12604

Catalog No. 89-115-938

Description

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM

Sequence: SGIHS

Specifications

• Antigen: CTNNB1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of CTNNB1.
• Formulation: In TBS, pH 7.2 (BSA, 10% Proclin300)
• Gene Alias: CTNNB/DKFZp686D02253/FLJ25606/FLJ37923
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes ∼88 KDa of human CTNNB1.
• Content And Storage: Store at 4°C. For long term storage store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CTNNB1
• Gene Symbols: CTNNB1
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S33/S37 of human CTNNB1.
• Regulatory Status: RUO
• Gene ID (Entrez): 1499
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only