CTNNB1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of CTNNB1.
Manufacturer: Abnova Corporation PAB18856
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM
|ELISA (1:5000-1:20000) Western Blot (1:200-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:100) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to amino acids at internal region of human CTNNB1.|
|ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of CTNNB1.|
|In buffer containing 0.02% sodium azide, 2% BSA|
|Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Human, Murine, Rat|
For Research Use Only