CTTN Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of CTTN.
Supplier: Abnova Corporation PAB26793
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeqSequence: P-I-Yp-E-D
|Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed)
|Rabbit polyclonal antibody raised against synthetic peptide of CTTN.
|In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
|A synthetic peptide corresponding to residues surrounding Y421 of human CTTN.
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For Research Use Only