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Description
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
Specifications
Specifications
| Antigen | CXCR1 |
| Applications | Immunocytochemistry, Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of CXCR1. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (7-11 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | CXCR1 |
| Gene Accession No. | P25024 |
| Gene Alias | C-C/C-C-CKR-1/CD128/CD181/CDw128a/CKR-1/CMKAR1/IL8R1/IL8RA/IL8RBA |
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