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CXCR4 Rabbit anti-Bovine, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Polyclonal Antibody, Abnova™
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This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Specifications
Specifications
| Antigen | CXCR4 |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of CXCR4. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1.6 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | CXCR4 |
| Gene Accession No. | P61073 |
| Gene Alias | CD184/D2S201E/FB22/HM89/HSY3RR/LAP3/LCR1/LESTR/NPY3R/NPYR/NPYRL/NPYY3R/WHIM |
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