CYP2A6, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-577	100 μL

Catalog No. 89-126-577 Supplier Abnova Corporation Supplier No. PAB24904

Description

Rabbit polyclonal antibody raised against synthetic peptide of CYP2A6.

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq

Specifications

• Antigen: CYP2A6
• Applications: Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CYP2A6.
• Dilution: Western Blot (1:500-1:1000) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene: CYP2A6
• Gene Alias: CPA6/CYP2A/CYP2A3/P450C2A/P450PB
• Gene Symbols: CYP2A6
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to CYP2A6.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1548
• Test Specificity: CYP2A6 polyclonal antibody detects endogenous levels of CYP2A6 protein.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only