CYP3A4, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-116-768	100 μL

Catalog No. 89-116-768 Supplier Abnova Corporation Supplier No. PAB13615

Description

Rabbit polyclonal antibody raised against synthetic peptide of CYP3A4.

This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. [provided by RefSeq

Specifications

• Antigen: CYP3A4
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CYP3A4.
• Dilution: Western Blot (1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In TBS
• Gene: CYP3A4
• Gene Alias: CP33/CP34/CYP3A/CYP3A3/HLP/MGC126680/NF-25/P450C3/P450PCN1
• Gene Symbols: CYP3A4
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to human CYP3A4.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1576
• Target Species: Human
• Content And Storage: Store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only