MilliporeSigma™ Rabbit anti-Cytochrome p450 2J Family, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABS1605

Catalog No. ABS1605

Description

Specifically detects Cytochrome p450 2J Family in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting

Cytochrome P450 2J2 (EC 1.14.14.1; UniProt P51589; also known as Arachidonic acid epoxygenase, CYPIIJ2, Cytochrome P450 subfamily IIJ polypeptide 2, Flavoprotein-linked monooxygenase, Microsomal monooxygenase) is encoded by the CYP2J2 (also known as CPJ2) gene (Gene ID 1573) in human. Cytochromes P450 (CYP) proteins are primarily membrane-associated oxidases located either in the inner membrane of mitochondria or in the endoplasmic reticulum where they function as the terminal enzymes in electron transfer chains. In addition to processing endogenous substrates, CYPs also function to metabolize exogenous drugs and potentially toxic chemicals. The human CYP superfamily consisits of 57 genes and more than 59 pseudogenes divided into 18 families and 43 subfamilies. The CYP2J subfamily of enzymes are responsible for the epoxidation of endogenous arachidonic acid (AA) into epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE).

Specifications

• Antigen: Cytochrome p450 2J Family
• Classification: Polyclonal
• Gene Accession No.: P51589
• Host Species: Rabbit
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Serum

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
• Gene Symbols: CYP2J2; CPJ2
• Immunogen: Linear peptide corresponding to an internal sequence from the C-terminal half of human cytochrome p450 2J2.
• Quantity: 100 μL
• Research Discipline: Signaling
• Gene ID (Entrez): NP_000766
• Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

For Research Use Only