DAXX Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of DAXX.

Supplier:  Abnova Corporation PAB10002

Catalog No. 89-114-543

Description

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: DAXX
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of DAXX.
• Formulation: In 20mM KH₂PO₄, 150mM NaCl, pH 7.2 (0.01% sodium azide)
• Gene Accession No.: NP_001341;Q9UER7
• Gene Symbols: DAXX
• Immunogen: A synthetic peptide corresponding to amino acids 261-274 of human DAXX.
• Regulatory Status: RUO
• Gene ID (Entrez): 1616
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:7000-1:45000) Western Blot (1:200-1:2000) The optimal working dilution should be determined by the end user.
• Gene: DAXX
• Gene Alias: BING2/DAP6/EAP1/MGC126245/MGC126246
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only