DAXX Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-116-116	100 μg

Catalog No. 89-116-116 Supplier Abnova Corporation Supplier No. PAB12829

Description

Rabbit polyclonal antibody raised against synthetic peptide of DAXX.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: DAXX
• Applications: Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of DAXX.
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: DAXX
• Gene Accession No.: CAG33366
• Gene Alias: BING2/DAP6/EAP1/MGC126245/MGC126246
• Gene Symbols: DAXX
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to C-terminus of human DAXX.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1616
• Test Specificity: A 120 KDa major band can be detected.
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only