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DAXX Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89119723 Shop All Abnova Corporation Products
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100 μg
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89-119-723 100 μg
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Catalog No. 89-119-723 Supplier Abnova Corporation Supplier No. PAB18150
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Rabbit polyclonal antibody raised against synthetic peptide of DAXX.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

Antigen DAXX
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of DAXX.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene DAXX
Gene Accession No. Q9UER7
Gene Alias BING2/DAP6/EAP1/MGC126245/MGC126246
Gene Symbols DAXX
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human DAXX.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1616
Test Specificity This antibody is specific to DAXX.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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