DAXX (phospho S671), Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of DAXX.

Supplier:  Abnova Corporation PAB4922

Catalog No. 89-131-645

Description

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: DAXX
• Classification: Polyclonal
• Description: death-domain associated protein
• Gene: DAXX
• Gene Alias: BING2, DAP6, EAP1, MGC126245, MGC126246
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1616
• Content And Storage: Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.

• Applications: Dot Blot, ELISA
• Conjugate: Unconjugated
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_001341;Q9UER7
• Gene Symbols: DAXX
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S671 of human DAXX.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

For Research Use Only