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DAXX (phospho S671), Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of DAXX.

Supplier:  Abnova Corporation PAB4922

Catalog No. 89-131-645

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.


Description

Description

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

Specifications

DAXX
Polyclonal
death-domain associated protein
DAXX
BING2, DAP6, EAP1, MGC126245, MGC126246
Rabbit
Protein A purification
RUO
1616
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Dot Blot, ELISA
Unconjugated
In PBS (0.09% sodium azide)
NP_001341;Q9UER7
DAXX
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S671 of human DAXX.
400 μL
Primary
Human
Purified
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