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Description
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq
Specifications
Specifications
| Antigen | DES |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | SP138 |
| Conjugate | Unconjugated |
| Description | Rabbit monoclonal antibody raised against synthetic peptide of DES. |
| Dilution | Western Blot (1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.6 (1% BSA, 0.09% sodium azide) |
| Gene | DES |
| Gene Alias | CMD1I/CSM1/CSM2/FLJ12025/FLJ39719/FLJ41013/FLJ41793 |
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