DMPK, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-593	100 μL

Catalog No. 89-126-593 Supplier Abnova Corporation Supplier No. PAB24919

Description

Rabbit polyclonal antibody raised against synthetic peptide of DMPK.

The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]

Specifications

• Antigen: DMPK
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of DMPK.
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene: DMPK
• Gene Alias: DM/DM1/DM1PK/DMK/MDPK/MT-PK
• Gene Symbols: DMPK
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to DMPK.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1760
• Test Specificity: DMPK polyclonal antibody detects endogenous levels of DMPK protein.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only