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Description
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
Specifications
Specifications
| Antigen | DNM1 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of DNM1. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide) |
| Gene | DNM1 |
| Gene Alias | DNM |
| Gene Symbols | DNM1 |
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