DNMT3A Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of DNMT3A.

Supplier:  Abnova Corporation PAB2204

Catalog No. 89-123-748

Description

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: DNMT3A
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of DNMT3A.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_072046;Q9Y6K1
• Gene Symbols: DNMT3A
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human DNMT3A.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: DNMT3A
• Gene Alias: DNMT3A2/M.HsaIIIA
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1788
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only