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DOK1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115247 Shop All Abnova Corporation Products
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89-115-247 100 μL
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Catalog No. 89-115-247 Supplier Abnova Corporation Supplier No. PAB11640

Description

Rabbit polyclonal antibody raised against synthetic peptide of DOK1.

Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq

Specifications

Antigen DOK1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of DOK1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene DOK1
Gene Alias MGC117395/MGC138860/P62DOK
Gene Symbols DOK1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human DOK1.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1796
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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