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DOK1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of DOK1.

Supplier:  Abnova Corporation PAB12821

Catalog No. 89-116-113


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Description

Description

Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq

Specifications

Specifications

DOK1
Polyclonal
Rabbit polyclonal antibody raised against synthetic peptide of DOK1.
In PBS (0.02% sodium azide)
AAC51127
DOK1
A synthetic peptide corresponding to C-terminus of human DOK1.
RUO
1796
Human
Liquid
Immunocytochemistry, Western Blot
Unconjugated
Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
DOK1
MGC117395/MGC138860/P62DOK
Rabbit
100 μg
Primary
A 62 KDa band should be detected.
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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