DUSP14 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of DUSP14.

Supplier:  Abnova Corporation PAB4143

Catalog No. 89-131-291

Description

In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80; MIM 112203) and B7-2 (CD86; MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2; MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4; MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM

Specifications

• Antigen: DUSP14
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of DUSP14.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_008957;O95147
• Gene Symbols: DUSP14
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human DUSP14.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: DUSP14
• Gene Alias: MKP-L/MKP6
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 11072
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only