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DYRK1A Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of DYRK1A.

Manufacturer:  Abnova Corporation PAB2068

Catalog No. 89-122-181


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Description

Description

This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq

Specifications

Specifications

DYRK1A
Unconjugated
Western Blot (1:1000) The optimal working dilution should be determined by the end user.
DYRK1A
Liquid
DYRK1A
A synthetic peptide (conjugated with KLH) corresponding to internal region of human DYRK1A.
400 uL
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human
ELISA, Western Blot
Rabbit polyclonal antibody raised against synthetic peptide of DYRK1A.
In PBS (0.09% sodium azide)
NP_001387;Q13627
DYRK|DYRK1|HP86|MNB|MNBH
Rabbit
Protein A purification
RUO
Primary
1859
Documents
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