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Description
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | EDA |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of EDA. |
| Dilution | ELISA (1:1000) Western Blot (1:50-100) Immunohistochemistry (1:10-50) Flow cytometry (1:10-50) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | EDA |
| Gene Accession No. | NP_001390;Q92838 |
| Gene Alias | ED1/ED1-A1/ED1-A2/EDA1/EDA2/HED/XHED/XLHED |
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