EDA2R, Rabbit, Polyclonal Antibody, Abnova™

Rabbit Polyclonal antibody raised against recombinant EDA2R.

Supplier:  Abnova Corporation PAB12963

Catalog No. 89-116-224

Description

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq

Specifications

• Antigen: EDA2R
• Classification: Polyclonal
• Description: Rabbit Polyclonal antibody raised against recombinant EDA2R.
• Formulation: In PBS (0.02% sodium azide)
• Gene Accession No.: AAQ89953
• Gene Symbols: EDA2R
• Immunogen: Recombinant protein corresponding to human EDA2R.
• Regulatory Status: RUO
• Gene ID (Entrez): 60401
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: EDA2R
• Gene Alias: EDA-A2R/EDAA2R/TNFRSF27/XEDAR
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only